Villedieu-le-Château (French pronunciation: [vildjø lə ʃɑto]) is a commune in the Loir-et-Cher department in central France.

Villedieu-le-Château borders the commune of La Chartre-sur-le-Loir (Sarthe) and marks the most eastern extension of the department and of the Bas-Vendômois.

The Niclos stream traverses the commune.

The village is dominated by the medieval fortified enceinte of a ruined medieval monastic foundation established by the Abbey of the Trinity at Vendôme.

The cult of Our Lady of Pity was transferred to the 15th-century parish church, which possesses early painting on wood, and which is the site of an annual pilgrimage in September.