Villequiers (French pronunciation: [vilkje]) is a commune in the Cher department in the Centre-Val de Loire region of France.

An area of forestry and farming area comprising the village and several hamlets situated in the valley of the river Vauvise, about 19 miles (31 km) east of Bourges, at the junction of the D12 with the D93 and D72 roads.

The Vauvise flows north-northeast through the eastern part of the commune.