Vilvestre is a village and municipality in the province of Salamanca, western Spain, part of the autonomous community of Castile-Leon.

It is located 96 kilometres from the provincial capital city of Salamanca and has a population of 468 people.

It lies 592 metres above sea level and the postal code is 37258.

[1] Situated on the Río Duero, the climate is typical of the Mediterranean with orange and olive groves.

This article about a location in the province of Salamanca, Spain, is a stub.