In a career stretching from 1984 to 2002, he played for Stade Brestois 29, Matra Racing, Montpellier Hérault, Paris Saint-Germain, Heart of Midlothian in Scotland and, finally, with Red Star 93.

[citation needed] With France he won the UEFA Under 21 European Cup in 1988 (13 matches played), and earned 19 full international caps, scoring 2 goals, as well as participating at Euro 1996.

[citation needed] In 1997, the French Football Federation moved to suspend Guérin after he failed a drugs test administered after a PSG game on 5 October.

Guérin subsequently appealed to the French federal Administrative Court at Versaille, contesting the FFF's decision on several counts.

The court at Versailles upheld one of Guérin's contentions, that the drugs test was improperly administered, and thus decreed that the entire process should be deemed void.