Vincenzo "Enzo" Montefusco (born 26 April 1945 in Naples) is an Italian former football player and manager, who played as a midfielder.

He is most noted for his association with his hometown side Napoli, where he played for over a decade as a player.

During the late 1990s he also served three times as the club's caretaker manager, replacing Luigi Simoni, Giovanni Galeone and Renzo Ulivieri respectively.

He was ultimately sacked by Napoli following the club's promotion to Serie A at the end of the 1999–2000 season.

This biographical article related to association football in Italy, about a midfielder born in the 1940s, is a stub.