At the west end of downtown Martinsville, the eastbound highway turns north onto four-lane divided Market Street.

The two directions of the state highway come together at the intersection of Market and Fayette streets.

SR 457 passes under Franklin Street and crosses over the Dick & Willie Passage Rail Trail.

The state highway passes Martinsville High School and reduces to a two-lane undivided road at Fairy Street before reaching Chatham Road adjacent to Hooker Field, home of the Martinsville Mustangs of minor league baseball.

SR 457 turns north onto Chatham Road and leaves the city of Martinsville.