From 1971 onwards she had a career owning and running a successful vintage clothing store, Virginia, in Holland Park in London.

On television, she was a regular cast member in The Troubleshooters as Julie Serres, and played Dyoni in the Doctor Who serial The Daleks.

[3][4] Wetherell ran a vintage clothing shop, Virginia, at 98 Portland Road in Holland Park for 42 years, from 1971 to 2013.

[5] Her shop attracted customers from the fashion, film and theatrical industries: visitors to the shop and customers included singers Barbra Streisand and Madonna, actors such as Nicole Kidman, models such as Helena Christensen, Naomi Campbell, Kate Moss and Susie Cave, and fashion designers such as John Galliano, Donatella Versace, Donna Karan, Ralph Lauren and Alberta Ferretti, who took inspiration from her vintage clothes.

[1] Wetherell was interviewed, as Virginia Bates, about the shop and vintage clothing in ITV4's television presentation of the 2024 Goodwood Revival, broadcast on 18 September 2024.