As a teenager she studied at the Lycée Pasteur, a school for French Brazilians, where she met Alec Haiat, Yann Laouenan, Daniel "Dany" Roland, Marcel Zimberg and Xavier Leblanc; with them she founded, in 1978, the experimental/progressive rock band A Gota Suspensa.

After releasing a self-titled album in 1983, they decided to shift their musical direction towards a more accessible new wave sound inspired by Blondie, Laurie Anderson and Rita Lee, among others, and in the following year, they changed their name to Metrô.

In 1988, the same year Metrô first disbanded, Virginie served as a guest musician on comedy rock band João Penca e Seus Miquinhos Amestrados' third album, Além da Alienação, on the track "Sem Ilusões".

She also formed the short-lived solo project Virginie & Fruto Proibido alongside Don Beto (guitar), Nilton Leonardi (bass) and Albino Infantozzi (drums); their only release was the album Crime Perfeito.

[9][10] Prior to focusing on her musical career, Virginie was a model (she has posed for magazines such as Vogue and Claudia) and originally planned to be an actress; she has appeared in the 1981 telenovela Os Imigrantes as Irma, and as herself in Lael Rodrigues' Rock Estrela and Francisco de Paula's Areias Escaldantes, both from 1985.