Virosome

[1] A safely killed virus can serve as a promising vector because it won't cause infection and the viral structure allows the virosome to recognize specific components of its target cells.

Inside of the virosome, there is a central cavity that holds the therapeutic molecules such as nucleic acids, proteins, and drugs.

Virosomes are suspended in saline buffers and are administered through respiratory, parenteral, intravenous, oral, intramuscular, and topical routes.

[2] In contrast to liposomes, virosomes contain functional viral envelope glycoproteins: influenza virus hemagglutinin (HA) and neuraminidase (NA) intercalated in the phospholipid bilayer membrane.

[8] The benefits of virosomes are that the specific structure and small size help with the precision of target cells.

However, glycoproteins can still induce a prophylactic response against the virus, which helps with establishing virosomes as vaccine delivery systems.