Virtual Cell

Models can range from the simple to the highly complex, and can represent a mixture of experimental data and purely theoretical assumptions.

The graphical user interface allows construction of complex models in biologically relevant terms: compartment dimensions and shape, molecular characteristics, and interaction parameters.

VCell allows users a choice of numerical solvers to translate the mathematical description into software code which is executed to perform the simulations.

The VCell Database uses an access control system with permissions to allow users to maintain their models private, share them with select collaborators or make them public.

VCell supports the following features: VCell allows users integrated access to a variety of sources to help build and annotate models: The Virtual Cell is being developed at the R. D Berlin Center for Cell Analysis and Modeling at the University of Connecticut Health Center.

VCell Models can be formulated as reaction networks or based on reaction rules. A model can be simulated using many physical assumptions: deterministic, stochastic or hybrid deterministic/stochastic; non-spatial compartmental, simulating only reaction kinetics, or with explicit spatial geometries accounting also for diffusion and flow. A new experimental feature allows for reaction-diffusion models in changing geometries (top).