In 2010, she lost the final of the Portugal Open with Aurélie Védy to opponents Anabel Medina Garrigues and Sorana Cîrstea.

Diatchenko also participated in events on the ITF Circuit: she won the tournament in Darmstadt, Germany, where she defeated eighth-seeded German player Julia Schruff in the final.

Then she lost her fourth WTA Tour doubles final with partner Tatiana Poutchek, at Copenhagen to German pair Anna-Lena Grönefeld/Julia Görges.

Diatchenko qualified for the Wimbledon Championships for the first time in her career by defeating Julia Glushko, Maria Elena Camerin and Stéphanie Dubois for her first main draw in a Grand Slam tournament.

Vitalia was also defeated in the first round of the women's doubles with compatriot Maria Kondratieva, by Vera Dushevina and Ekaterina Makarova.

On July 30, Diatchenko won the biggest singles title of her career so far at the President's Cup, an $100k tournament held in Astana.

In the doubles, after winning their first round and quarterfinal matches, Vitalia and Alexandra upset third seeds Evgeniya Rodina and Valeria Solovyeva in the semifinals.

Due to suffering an injury in the semifinal match of the singles, Vitalia was unable to play the doubles final.

After a brief appearance on the WTA Tour and a return to the ITF Circuit, she played her first notable game for years at the Kremlin Cup, where the 140-ranked Vitalia eliminated No.

[6] Only main-draw results in WTA Tour, Grand Slam tournaments, Fed Cup/Billie Jean King Cup and Olympic Games are included in win–loss records.