He started publishing in Venice, where he was born, and later moved to Ferrara, joining the court of Duke Alfonso II d'Este in mid-to-late 1582, where he was the official ducal music printer.
He may have met the duke through Giulio Cesare Brancaccio, whose translation and commentary on Julius Caesar's Commentarii de Bello Gallico Baldini printed in early 1582.
[1] His first work as ducal music printer, and indeed his first print of music, was an anthology of madrigals, Il lauro secco (1582), written by the most renowned composers of Rome and Northern Italy, as well as introducing important new composers, and was inspired by Laura Peverara.
[3] Baldini published very little music for Alfonso between 1586 and 1594, and began publishing regularly again 1594–1596, when he printed anthologies containing madrigals by some of the most important madrigalists of the seconda pratica, including Luzzasco Luzzaschi, Carlo Gesualdo, and Alfonso Fontanelli, all of whom were part of the Este court at the time.
"[5] During this period he printed descriptions and texts for various intermezzos and other theatrical entertainments.