Vladimir Mikhailovich Myasishchev (Russian: Владимир Михайлович Мясищев; 28 September 1902 – 14 October 1978) was a Soviet aircraft designer, major general of Engineering (1944), Hero of Socialist Labour (1957), Doctor of Technical Sciences (1959), Honoured Scientist of the RSFSR (1972).

In 1940, after his release, Myasishchev headed a design bureau (in the same building), working on the long-range high-altitude bomber DVB-102 (ДВБ-102).

In 1946–1951, Myasishchev was the head of the faculty and later dean of the Department of Aircraft Design at Moscow Aviation Institute.

In 1967–1978, Myasishchev held a post of the chief aircraft designer of the Experimental Machine Building Plant, which would bear his name starting 1981.

Granddaughter — Daria Myasishcheva (the common-law wife and mother of the children of Russian actor Pavel Derevyanko).