During the NATO bombing of Yugoslavia in 1999, Radmanović played at the Nike Hoop Summit in Tampa for which he was called up during the regular season.

He averaged 11.8 points per game and 4.6 rebounds, helping the Sonics win their first-round playoff matchup against the Sacramento Kings.

After voicing his frustration for not being a starter, on February 14, 2006, Radmanović was traded from the SuperSonics to the Los Angeles Clippers for power forward Chris Wilcox.

Although the Lakers were offering the same amount of money as Clippers, Radmanović was persuaded to join the team by Kobe Bryant, Phil Jackson, Magic Johnson and his good friend, Vlade Divac, who were all convinced his shooting and playing opportunities would greatly increase in the Lakers' triangle offense.

Jackson has also called Vladimir a "space cadet" and "my favorite Martian" in reference to his being out of position and taking wild three-point shots.

On February 18, 2007, Radmanović told the Lakers that he had separated his shoulder, when he fell on a patch of ice in Park City, Utah, the day before, during the weekend of the 2007 NBA All-Star Game and would be out for approximately eight weeks.

[7] Radmanović's Lakers contract banned him from taking part in activities that involve significant risk of injury, including skiing and snowboarding.

On February 7, 2009, Radmanović was traded to the Charlotte Bobcats in exchange for forward Adam Morrison and guard Shannon Brown.

[9] On November 16, 2009, Radmanović was traded to the Golden State Warriors along with Raja Bell in exchange for Stephen Jackson and Acie Law.

Radmanović was set to debut for the senior national team at the 2001 EuroBasket but he turned down a call-up from coach Svetislav Pešić in order to focus on preparing to enter the NBA.

[16] Radmanović made his debut for the senior side at the 2002 FIBA World Championship in Indianapolis where Yugoslavia won gold.

[18] Radmanović skipped out on the 2003 EuroBasket[19] but he did take part in the 2004 Olympic tournament where Serbia and Montenegro was eliminated in the preliminary round.

Radmanović was coming off of an excellent season with Seattle and the return of Željko Obradović as national team head coach brought back enthusiasm to both players and fans alike.