Vlatko Hercegović (Serbian Cyrillic: Влатко Херцеговић; c. 1428–1489), was the second and the last Herzog of Saint Sava, succeeding his father Stjepan Vukčić in 1466.

On 21 May 1466, the old and terminally ill duke dictated his last words, recorded in a testament, and bypassing Vladislav he condemned him by saying that it was him who "brought the great Turk to Bosnia to the death and destruction of us all".

[4] Počitelj fell in 1471, however, herceg Vlatko already in 1470 realized that only radical change in his politics could bring him some release, so he pursued and achieved a peace with the Ottomans.

[5] Just before the death of Sultan Mehmed II, Vlatko tried one more push to the heart of Bosnia, but abandoned by his allies his venture ended in disaster, after which he completely and finitely withdraw to his fortress in Novi.

In November 1481, Ajaz-Bey of the Sanjak of Herzegovina besieged Novi, however, just before 14th December of 1481 Vlatko gave up resisting, and agreed with the Ottomans to move with his family to Istanbul.