[2] The park adjoins El Jabalí Flora and Fauna Protection Area on the southwest.

Bosque Mesófilo Nevado de Colima State Park in Jalisco is composed of four separate enclaves which adjoin the national park on the east and west flanks of the two peaks.

[1] Plant communities include high-elevation pine forests, and subalpine grassland, called zacatonal, at the highest elevations.

[2] Native mammals include white-tailed deer (Odocoileus virginianus), puma (Puma concolor), coyote (Canis latrans), and collared peccary (Pecari tajacu).

[2] 102 species of birds have been recorded in the park, including the long-tailed wood partridge (Dendrortyx macroura), white-striped woodcreeper (Lepidocolaptes leucogaster), russet nightingale-thrush (Catharus occidentalis), brown-backed solitaire (Myadestes occidentalis), gray silky-flycatcher (Ptiliogonys cinereus), chestnut-sided shrike-vireo (Vireolanius melitophrys), golden-browed warbler (Basileuterus belli), red warbler (Cardellina rubra), crescent-chested warbler (Oreothlypis superciliosa), rufous-capped brushfinch (Atlapetes pileatus), green-striped brushfinch (Arremon virenticeps), and collared towhee (Pipilo ocai).