Divided into 25 administrative districts, the region is multi-ethnic [6] and multilingual, including groups such as the Ewe, the Guan, and the Akan people.

The Guan peoples include the Lolobi, Likpe, Akpafu, Akyode, Buem, Nyagbo, Avatime, and Nkonya.

[7] This group includes the Ewes, Guans and other minor tribes living in the Volta Region.

[citation needed] The people of the Volta Region are popular known for their rich cultural display and music some of which include Agbadza, Borborbor and Zigi.

Under this administration system, the region is divided into 18 MMDA's (made up of 0 Metropolitan, 6 Municipal and 12 Ordinary Assemblies).

The current list is as follows: The following districts are now within the boundaries of the Oti Region which was formally created on 15 February 2019.

The native and dominant ethnic group, the Ewe people, were divided between the two Togos.