Vranje (Serbian Cyrillic: Врање, pronounced [ʋrâɲɛ] ⓘ) is a city in Southern Serbia and the administrative center of the Pčinja District.

[12] Some time before 1306, tepčija Kuzma was given the governorship of Vranje (a župa, "county", including the town and neighbouring villages), serving King Stefan Milutin.

[16] By the time of the proclamation of the Serbian Empire, holders with the title kefalija are present in Vranje, among other cities.

[17] During the fall of the Serbian Empire, Vranje was part of Uglješa Vlatković's possessions, which also included Preševo and Kumanovo.

[12] Good mercantile relations with developing mine city Novo Brdo led to creation of numerous settlements.

[12] Vranje was part of the Ottoman Empire until 1878, when the town was captured by the Serbian army commanded by Jovan Belimarković.

[18] During the Serbian–Ottoman Wars (1876–1878), most of the Albanian population of Vranje was forced to flee to the Ottoman vilayet of Kosovo and others Muslims such as Turks fled from the city as well.

[12] Up until the end of the Balkan Wars, the city had a special position and role, as the transmissive station of Serbian state political and cultural influence on Macedonia.

As a border town of the Kingdom of Serbia, it was used as the starting point for Serbian guerrilla (Chetniks) who crossed into Ottoman territory and fought in Kosovo and Macedonia.

King Peter I Karađorđević, Prime Minister Nikola Pašić and the chief of staff General Radomir Putnik stayed in Vranje.

Vranje was occupied by the Kingdom of Bulgaria on 16–17 October 1915, after which war crimes and Bulgarisation was committed on the city and wider region.

[12] The Pčinja District also includes the municipalities of Bosilegrad, Bujanovac, Vladičin Han, Preševo, Surdulica, and Trgovište.

This original music style has been renewed recently by taking different, specific, and more oriental form, with the contribution of rich brass instruments.

Vranje lies close to Besna Kobila mountain and Vranjska Banja, locations with high potential that are underdeveloped.

Other locations in and around Vranje with some tourist potential include Prohor Pčinjski monastery, Kale-Krševica, Markovo kale, Pržar, birth-house museum of Bora Stankovic.

In those years, many factories were opened, such as the Tobacco Industry of Vranje (Serbian: Дуванска индустрија Врање), Simpo, Koštana (shoe factory), Yumco (cotton plant), Alfa Plam (technical goods), SZP Zavarivač Vranje and others.

Among the companies with business locations in the city are British American Tobacco, Simpo, Sanch, Mladenovic D.O.O, Kenda Farben, Danny style, OMV and Hellenic Petroleum.

[29] The following table gives a preview of total number of registered people employed in legal entities per their core activity (as of 2022):[30] The city of Vranje is twinned with: