From the latter half of the 16th century, there was a postal station in Wöllstein on the Dutch Post Route running from Brussels (nowadays in Belgium rather than the Netherlands) by way of Rheinhausen and Augsburg to Innsbruck, Trent and Italy.

[4] After consolidation and the founding of the Imperial Post (Kaiserliche Reichspost) in 1597, the Wöllstein postal station was still open for business, but beginning in the late 17th century, owing to route changes and cities’ growing influence, it slowly lost its importance.

The wheel on the dexter (armsbearer's right, viewer's left) side is the Wheel of Mainz, a reference to Wöllstein's former allegiance to Electoral Mainz, and the lion rampant on the sinister (armsbearer's left, viewer's right) side is taken from the arms once borne by the County of Nassau-Saarbrücken, forming another reference to a former territorial allegiance.

There are links to bus routes run by Omnibusverkehr Rhein-Nahe (ORN) and the Verkehrsgesellschaft Bad Kreuznach.

Several times daily, buses run the route from Wöllstein by way of Siefersheim, Wonsheim and Wendelsheim to Alzey, and in the opposite direction there is the odd bus to Wörrstadt.

Located in Wöllstein are the JUWÖ Poroton Werke (hollow bricks), Meralux (doors and windows), the institutional kitchen supplier Jomo and a Lidl distribution centre.