Wallace Bruce Fye (born 1946) is an American retired cardiologist, medical historian, writer, bibliophile and philanthropist.

he later donated many of the books and papers he had collected over the previous 50 years to the Mayo Clinic, the Huntington Library, San Marino, California, and the Alan Mason Chesney Archives of the Johns Hopkins Medical Institutions, Baltimore, Maryland.

[1] During his tenure as a Robert Wood Johnson Clinical Scholar at Hopkins, he completed his cardiology training and received an MA degree in 1978 from the Institute of the History of Medicine.

[1] In 1978, Fye was elected a fellow of the American College of Cardiology (ACC)[4] and in the same year joined the Marshfield Clinic in Wisconsin, where he founded the echocardiography laboratory.

[2][5] Of a number of reviews, historian Philip Pauly wrote, Fye outlines the emergence of the discipline of physiology in American within the framework of a late nineteenth century medical reform movement.

These were reprinted in a book titled Profiles in Cardiology which was co-edited with J. Willis Hurst and C. Richard Conti and published by Mahwah, NJ: Foundation for Advances in Medicine and Science (2003).

[11][12] During his tenure as president of the ACC, between 2002 and 2003,[4] Fye tackled some of the effects of Clinton health care plan of 1993, which had highlighted the high number of specialists and a need for generalists, with the result that between 1994 and 2000, fellowship appointments fell by nearly a third.

He coordinated a luncheon symposium on collecting medical books at the 1977 meeting of the American Association for the History of Medicine and published his first article on the subject two years later.

The series was launched with an original volume William Osler's Collected Papers on the Cardiovascular System, which Fye edited.

In so doing, Fye has created a highly readable story of modern medicine in twentieth-century America, meeting the challenge of appealing to professional historians, clinicians, and interested public alike.

[24] In 2021, Fye arranged to donate his private papers to the Alan Mason Chesney Archives of the Johns Hopkins Medical Institutions, Baltimore, Maryland,[25] and donated what was believed to be the largest private collection of books and other materials related to the history of cardiology to the Huntington Library, San Marino, California.

[26] Fye met Lois Baker in high school in Bucks County, Pennsylvania, and they married whilst he was a medical student and she was a nurse at Johns Hopkins.