WEUP-AM first broadcast from a pink trailer in the grounds of Syler Tabernacle Church in Huntsville, before moving to its present studios on Jordan Lane.
The station's format was a mixture of urban contemporary gospel and soul music as well as news and public affairs catering to the interests of the Tennessee Valley's black population, everyday from sunrise to 6 p.m.
The Garretts made history when they testified before a congressional committee in 1963, the outcome of which resulted in the change of a Federal Communications Commission law regulating 24-hour broadcasts in the 1960s.
They continued to expand the station's audience by acquiring WHIY (1190 AM, now WEUV) and WXKI (103.1 FM, now WEUP-FM), both licensed to Moulton, Alabama, in 1989.
The stations were sold to Hundley Batts and Virginia Caples as part of a two-station deal by Moulton Broadcasting Co. Inc. (WHIY) and Lawco FM Ltd.