The station's construction permit was originally granted on November 30, 1989, as W29BA, operating on channel 29, which would be licensed to nearby Lawrence.

In 2001, the station was upgraded to Class A status as WVXN-CA and dropped home shopping programming in favor of affiliating with MTV2.

Longtime owner Randolph Weigner agreed to sell WFXZ to Prime Time Partners in December 2011.

[2] The station became a charter MundoFox affiliate when the network formally launched on August 13, 2012,[7] with Azteca America programming moving to its second digital subchannel; it returned to primary status early on December 1, 2016, due to MundoMax ending operations (shortly after Fox International Channels dropped out of the joint venture in 2015).

[8] In the FCC's incentive auction, WFXZ-CD sold its spectrum for $63,949,770 and indicated that it would enter into a post-auction channel sharing agreement.