It also broadcasts in HD Radio; HD1 rebroadcasts the analog signal while HD2 is a feed of WVTF Music.
WISE-FM is one of three stations whose call signs spell out their city of license; the others are WACO-FM and WARE.
WISE-FM and its translators were previously full-time repeaters of Virginia Tech's Radio IQ news and public affairs network, based at WVTF in Roanoke.
WEHC also carries Radio IQ for part of the day, but breaks from the network in afternoons and evenings (1–4 p.m. and 6 p.m. to midnight) to air its own locally-focused talk, music, and sports programming.
[6][7] In addition to the main station, WISE-FM is relayed by FM translators to widen its broadcast area.