The three stations share studios on College Avenue Southeast in Grand Rapids; WOOD-TV's transmitter is located southwest of Middleville.

In addition to its main signal, WOOD-TV operates Class A digital translator WOGC-CD (UHF channel 25), licensed to Holland with a transmitter in Zeeland.

There is also a digital repeater on channel 34, also licensed to Grand Rapids, with a transmitter in the Wolf Lake section of Egelston Township.

On October 19, WLAV-TV changed its call letters to WOOD-TV to match its radio sister and began airing from a new transmitter in northeastern Grand Rapids.

During the FCC's licensing freeze the commission developed channel allocation and separation to eliminate interference between stations with the same frequency.

All of the Bitner Group's stations were then sold, for a then-record-breaking $16 million, to Time Inc. in 1957, who later subordinated their acquisition under its in 1961 established subsidiary Time-Life, Inc.– as Time–Life Broadcasting, Inc. at first.

LIN TV reacquired WOOD-TV and its LMA with WOTV in 1999 when AT&T sold-off its stake in the company to Hicks, Muse, Furst, and Tate (now HM Capital).

[5] The deal closed on December 19, bringing WOOD, along with WOTV and WXSP-CD, under common ownership with CBS affiliate WLNS-TV in Lansing.

The combined company will be known as Nexstar Media Group, and will own 171 stations, including WOOD-TV, serving an estimated 39% of households.

[8] On December 3, 2018, Nexstar announced it would acquire the assets of Tribune Media (owners of Fox affiliate WXMI) for $6.4 billion in cash and debt.

[21] WOOD-TV presently broadcasts 44 hours of locally produced newscasts each week (with seven hours each weekday and 4+1⁄2 hours each on Saturdays and Sundays); in addition, the station produces a half-hour public affairs program To the Point with Rick Albin, which airs Sundays at 10 a.m.; a 25-minute sports highlight program Sports Overtime, which airs Sundays after the 11 p.m. newscast; and Football Frenzy, a weekly highlight program on Friday nights during the fall which covers high school football games as well as other sports news of the day (the 11 p.m. newscast is shortened to allow Football Frenzy to air during the regular time slot).

The entertainment and lifestyle magazine show eightWest premiered on October 5, 2009, and airs weekday mornings at 11 a.m. for an hour, as well as being streamed live on the station's website.

Also on that date, WOOD-TV became the second station in southwestern Michigan to begin broadcasting its local newscasts in 16:9 widescreen enhanced definition.

Starting in September 2011, WOOD-TV began broadcasting all of its newscasts during ArtPrize from a temporary studio built inside the Grand Rapids Art Museum.

In July 2022, WOOD-TV was one of two Michigan television stations to inadvertently publish test results related to the state's primary election.

Later that week, WOOD-TV news director Stanton Tang admitted he urged Fox to write and distribute the memo; journalists at the station called for his firing.

[26] The controversy ultimately prompted Nexstar to issue a formal apology, and Fox and Tang were removed from discussions about WOOD-TV's future Pride Month news coverage.

[27] Two weeks after the investigation started, Fox and Tang were fired, along with Madeline Odle and Luke Stier, two longtime executive producers who disagreed with the memo.