This process began in 1914 when facilities were moved to their current location in St. Louis's Central West End neighborhood in 1914, and was completed in 1918 with the official naming of the School of Medicine.

[2] Of note, the first female faculty member is believed to have been biochemist and physiologist Ethel Ronzoni Bishop, who became an assistant professor in 1923.

[3] The Medical School began its escalation from regional renown in the 1940s, a decade when two groups of faculty members received Nobel Prizes, in 1944 and 1947.

Professors Carl and Gerty Cori became Washington University's fifth and sixth Nobel laureates for their discovery of how glycogen is broken down and resynthesized in the body.

[2] In March 2020, Washington University School of Medicine announced the construction of a new $616 million, 11-story, 609,000-square-foot neuroscience research building which will sit at the eastern edge of the Medical Campus in the Cortex Innovation Community.

[5] Washington University Medical Campus comprises 186 acres (75.3 ha) spread over about 18 city blocks, located along the eastern edge of Forest Park within the Central West End neighborhood of St. Louis.

The complex is accessible via the Central West End MetroLink station, which provides transportation to the rest of Washington University's campuses.

15 faculty members have MERIT status, a special recognition given by the National Institutes of Health that provides long-term, uninterrupted financial support to investigators.