[3] The station is the network's longest serving Georgia affiliate after Fox dropped WATL for New World-owned WAGA-TV in Atlanta.

Originally, WXTX aired programming from MyNetworkTV on weeknights from 11 p.m. to 1 a.m. For Saturday night prime time, that network was shown early Sunday mornings from 12:30 to 2:30 a.m.

Since 2004 through a news share agreement, WTVM has been producing the Chattahoochee Valley's only prime time newscast on WXTX called Fox 54 News at 10, which airs weeknights for an hour (thirty minutes on weekends) from the ABC affiliate's facility on Wynnton Road/SR 22 Spur in the Dinglewood section of Columbus.

WXTX's newscasts have a separate music package and graphics theme from WTVM and employs the use of the ABC affiliate's primary set but modified with duratrans indicating the Fox-branded show.

In late-October 2010, HD-ready graphics began to be seen in weather forecasting segments indicating WTVM and WXTX would be making the switch to high definition newscasts.

Since Alabama (which is in the Central Time Zone) is an hour behind Georgia, this program is the only local news catering to viewers on the western side of the market airing at 6 p.m. Viewers in those areas also have access to stations from Dothan and Montgomery offering broadcasts geared for the Central Time Zone.