Its programs can also be heard in Houghton on WXXY (90.3 FM) and on the seventh digital subchannel of WXXI-TV (channel 21).

On July 2, 1984, WXXI-FM shifted most of its news programming, including NPR's Morning Edition and All Things Considered, to its new second service, WXXI (1370 AM).

With the exception of some weekend and evening specialty programming, WXXI-FM became a full-time classical music service.

[9] WXXO originates broadcasts of the Rochester Philharmonic Orchestra, hosted by Brenda Tremblay.

WXXO also originates the national program With Heart and Voice, hosted first by Richard Gladwell and currently by Peter DuBois.