The interior features two mosaics on the right and left hand walls, and a large stained glass window.

In 1896,[2] Jeptha H. Wade II decided to fund the construction of a new receiving vault and chapel, dedicated to the memory of his grandfather, at Lake View Cemetery.

[3][4] Wade asked the newly-founded Cleveland architectural firm of Hubbell & Benes to create a preliminary design.

[2][3][4] There was a slight hill here,[5][6] and the structure was designed so that the crypt level could not be seen from the driveway that led to the front of the chapel.

[3] The hillside was excavated 25 feet (7.6 m) down to bedrock,[7] and the foundations and crypt level finished in late December 1898.

[14] A low gable roof covers the chapel and portico, and features a pediment with an unadorned tympanum in front.

[16] A variety of granites were considered, including Concord, Hallowell, North Jay, Troy, Westerly, and Barre.

[19] The order was so large and important to the Barre granite industry that quarry owner William Barclay traveled to Cleveland in late 1898 to consult with the architects.

[7] Countersunk in an architrave over the chapel doors are the words "Erected in Memory of Jeptha H. Wade by his Grandson, A.D.

[2] The stained glass window, titled Resurrection[7] or Flight of the Soul, was designed by Tiffany artisan Agnes Northrop.

[2] The sedilia, ceiling lamps, altar rail, candlesticks atop the altar rail, lectern, and casket pedestal are all made of white Carrara marble,[7][24] often cut and carved with great delicacy and inlaid with colored glass, gold, and mother of pearl.

[7] Smaller clerestory windows of white frosted glass set in a heavy bronze grille are positioned above the chapel doors.

[2] An anonymous writer for American Stone Trade praised Wade Memorial Chapel in 1916 as an "exquisite Greek temple".

[20] The industry journal focused particularly on the chapel's construction, noting, "In every detail it is perfectly finished, permanently bedded and jointed and of material in every way suitable for the purpose for which it is used.

"[20] Alice Gould Pattinson of the American Federation of Arts called Wade Chapel one of the most notable monuments at Lake View.