Waikāne or Waikane (Hawaiian pronunciation: [vɐjˈkaːne]), also known as North Koʻolaupoko ([-koʔolɐwˈpoko]), is an area and census-designated place in the County of Honolulu, Hawaii, United States, on the island of Oʻahu.

Included within the district, south of North Koʻolaupoko, are the largest windward towns of Kāneʻohe, Kailua, and Waimānalo.

Waikāne lies mostly along the coastline of Kāneʻohe Bay and consists of several lush valleys that extend inland to the steep face of the Koʻolau pali (cliff).

This area differs from the towns, valleys, and ahupuaʻa of the southern part of Koʻolaupoko in that it is mostly undeveloped, decidedly rural in character, with many small farms.

A larger city and county park at Kualoa provides camping and picnic areas, a long narrow beach, and views of Mokoliʻi Islet.

The south side of Kualoa Regional Park faces onto Kāneʻohe Bay, and the east shore is a fringing reef off the Pacific Ocean coast of northeast Oʻahu.

The Waikane CDP encompasses much more than the location known as Waikāne, which is but one of several valleys comprising the north end of the Koʻolaupoko District.

Hawaii Department of Education operates Waiāhole Elementary School in Waikane CDP.