The Walker's Point Historic District is a mixed working-class neighborhood of homes, stores, churches and factories in Milwaukee, Wisconsin, with surviving buildings as old as 1849, including remnants of the Philip Best Brewery and the Pfister and Vogel Tannery.

[2] The NRHP nomination points out that Walker's Point was "the only part of Milwaukee's three original Settlements to reach the last quarter of the Twentieth Century with its Nineteenth and early-Twentieth Century fabric still largely intact," and ventures that "For something similar, one would have to travel to Cleveland or St. Louis if, indeed, so cohesive and broad a grouping of...structures still exists even in those cities.

In 1834 he staked a claim to 160 acres on the point of land south of the confluence of the Milwaukee and Menomonee Rivers, and built a crude cabin and trading post at what is now the east side of Fourth Street where it meets Bruce.

The ridge itself was covered with hawthorn and hazelnut bushes, and was traversed by two Indian paths heading for the river.

The large Philip Best Brewing Co. (which became Pabst) opened later, as did the Pfister and Vogel leather tannery.