Hosted at Durham House by the explorer and courtier Sir Walter Raleigh, he and Manteo assisted the scientist Thomas Harriot with the job of deciphering and learning the Carolina Algonquian language.
Early encounters with the natives were friendly, and, despite the difficulties in communication, the explorers were able to persuade "two of the savages, being lustie men, whose names were Wanchese and Manteo" to accompany them on the return voyage to London[3] to help describe the conditions in the New World.
Raleigh's priority, however, was not publicity but intelligence about his new land of Virginia, and he restricted access to the exotic newcomers, assigning the scientist Thomas Harriot the job of deciphering and learning the Carolina Algonquian language[7] using a phonetic alphabet of his own invention.
Manteo and Wanchese returned to the New World in April 1585, sailing with Sir Richard Grenville's expedition in The Tyger, reaching the warm waters of the Caribbean in just 21 days.
[12] By July 6, Grenville was worried enough to send John Arundell with Manteo as guide and interpreter to recover Wanchese, but the villagers at Dasamongueponke could not be persuaded to give him up.
[13] In April 1586, Wanchese finally severed his former good relations with the English, leaving Chief Manteo as the colonists' sole Indian ally.
[15] A character based on Wanchese is featured in the Lost Colony theater production and in the 1999 film The Legend of Two Path by Native Canadian actor Nathaniel Arcand.