His first regional tenure was in Yunnan province, serving successively as the party chief of Guandu District, Kunming, the head of the Kunming Political and Legal Affairs department, the head of the municipal Organization Department, and deputy party chief.

[citation needed] In September 2012, he moved out of Yunnan province and was named vice governor of Hubei.

On February 11, 2019, Wang was transferred to Xinjiang to serve as the head of the regional Political and Legal Affairs Commission (Zhengfawei).

[6] On March 22, 2021, the United States Treasury Department “... unveiled new sanctions against two Chinese officials in response to ‘serious human rights abuse’ against Uighur Muslims in Xinjiang.

The sanctions, which target Wang Junzheng, secretary of the Party Committee of the Xinjiang Production and Construction Corps, and Chen Mingguo, director of the Xinjiang Public Security Bureau, were rolled out in coordination with Canada and European allies.”[7][8] On 18 October 2021, he was transferred to southwest China's Tibet Autonomous Region and appointed Communist Party Secretary of Tibet, the top political position in the region.