Wang joined the Chinese Communist Party in 1926 and led peasant movements in districts and counties.

Then Wang started his military career during the Huangma Uprising, establishing the Northeast Hubei Base.

Wang was born to a small landlord family, whose fortunes gradually declined after his father's death when he was 6, and his mother's three years later.

He protected the main forces across the Ming River and met with the Central Red Army in Maogong.

Later, due to command confusion and supply shortage, the west road army lost continuously, suffering heavy damage.

[citation needed] After the Second Sino-Japanese War broke out, Wang Shusheng was chosen to be the deputy commander.

During the time in Yan'an, Wang Shusheng married a military doctor named Yang Ju.

In the June 1946, he assisted Li Xiannian to command the military district and led the left army across from Guangshui to Pinghan Railway, then went forwards to Wudang Mountain.