Wapwallopen is an unincorporated community in Conyngham Township, Luzerne County, Pennsylvania, United States.

It is named for a Lenni Lenape settlement that was established where Big Wapwallopen Creek feeds into the Susquehanna River.

The name derives from Lenape òphalahpink 'place of white wild hemp'.

[2][3][4] Pennsylvania Route 239 passes through the settlement.