The uprising was supported by General Juan José Flores, president of Ecuador, and by the Catholic Society of Bogotá, formed a year earlier for the political expression of the most conservative sectors of the country.
Still according to the official account, Eraso denounced Antonio M. Alvárez, military head of the Pasto forces just defeated by Alcántara Herrán at Buesaco, and General José María Obando in the assassination of Sucre.
On the basis of Eraso's declaration, a judge in Pasto ordered the arrest of Obando, the most likely candidate of the opposition party in the upcoming presidential elections.
Fearing a nationwide revolution, Márquez asked Ecuadoran President Juan José Flores for military aid in suppressing the revolt of Obando.
This was a Pyrrhic victory for the government, however, because the opposition now used the Ecuadoran intervention and the promises made to Ecuador as a call for a general uprising against Márquez.
One after another the Santanderista leaders in the provinces revolted: Manuel González in Socorro, José María Vezga in Mariquita, Juan José Reyes Patria in Sogamoso and Tunja, Padre Rafael María Vásquez in Vélez, Francisco Farfán in Casanare, Salvador Córdova in Antioquia, Francisco Carmena in Ciénaga and Santa Marta, Juan Antonio Gutiérrez de Piñeres in Cartagena, Lorenzo Hernández in Mompós and Tomás Herrera in Panama.
González proclaimed himself the supreme head of the independent state formed by the ex-provinces of Socorro, Tunja, Pamplona, Vélez and Casanare, and went with his army to take Bogotá.
He would have seized the unguarded Bogotá if General Juan José Neira, distinguished in the war of independence, had not rallied the citizens and government forces and defeated González in the Battle of Buenavista (or La Culebrera) in October.
Governor Lino de Pombo declared a state of siege and General Francisco Urdaneta, military chief of the garrison, mobilized the entire population for defense.
To raise the spirits of the defenders, a procession was held with the statue of Jesus of Nazareth of San Agustín, the same that had led the forces of Antonio Nariño in the War of Independence.
General Neira was carried on the shoulders of distinguished gentlemen and crowned with laurel in the Plaza Mayor, in the middle of an uproarious ovation.