It returned two Members of Parliament (MPs) to the House of Commons of the Parliament of the United Kingdom, elected by the first past the post system.
South Warwickshire was itself abolished in 1885, when the Redistribution of Seats Act 1885 replaced it with four new single-member constituencies: Nuneaton, Rugby, Stratford-on-Avon and Tamworth.
Shirley resigned by accepting the office of Steward of the Chiltern Hundreds, causing a by-election.
Greville succeeded to the peerage, becoming 4th Earl of Warwick and causing a by-election.
Seymour was appointed Comptroller of the Household, causing a by-election.