Traveling north to exit Ryderwood, the highway crosses Campbell Creek and enters Lewis County.
[2][19][20] An extension of the highway connecting Vader to SR 407 near Cathlamet was studied by the state legislature in 1973 but was not recommended for construction.
[8] The Washington State Transportation Improvement Board heard proposals in the early 1990s to decommission SR 506 and transfer control of the highway to the counties and local governments, which was opposed by residents due to high maintenance costs.
[24][25] The overpass carrying SR 506 over I-5 was closed on July 6, 2021, after a truck struck it and caused major structural damage.
Governor Jay Inslee declared a state of emergency and approved funds to replace the entire bridge.