St. Jerome High School, then called a College, was founded in 1865 by Reverend Dr. Louis Funcken and his brother Fr.

[5] By 1968, independent Catholic School Boards were operating in Kitchener, Waterloo, Galt, Preston, Hespeler, Bridgeport, New Hamburg, Maryhill, St. Agatha, Linwood, Elmira, and St. Clements.

[4] In 1997, the Waterloo County Separate School Board ceased to exist as a result of a second provincial amalgamation effort.

The Waterloo Catholic District School Board was incorporated in 1998 through the Education Act to oversee Catholic schools in the cities of Cambridge, Kitchener, and Waterloo, and the townships of Wilmot, Woolwich, North Dumfries, and Wellesley.

An estimate at the time indicated that roughly one in three students in the Region are educated by the Catholic Board.