The grounds and buildings of the hospital's 1909 campus were converted to become the North Carolina School of Science and Mathematics, which began classes in 1980.

[4] Watts donated another $500,000 for the new hospital site, designed by Boston architect Bertrand E. Taylor in the Spanish Mission style.

The hospital was enlarged in 1926 with the Valinda Beale Watts Pavilion, designed by the local architectural firm of Atwood and Nash.

The referendum passed, though Watts was ultimately closed in favor of an enlarged Lincoln Community Health Center.

[7] By 1922, Watts Hospital's quality of care and its philanthropic mission to provide healthcare to the working poor was so well-regarded that James B. Duke and North Carolina Governor Cameron Morrison proposed the creation of the state's first four-year medical college, Duke University, to educate students in conjunction with clinical services provided at Watts Hospital.