He appeared in Star Wars: Episode III – Revenge of the Sith, playing Grand Moff Tarkin in 2005, and in the TV show Lost in 2008.

Productions he has appeared in include The Resistible Rise of Arturo Ui (1985) and All's Well That Ends Well with Nimrod Theatre Company, as well as The Rocky Horror Show, Sweet Bird of Youth, King Lear, and The Threepenny Opera.

[6] In 2005, Pygram made a brief cameo appearance in Star Wars: Episode III – Revenge of the Sith as a young Grand Moff Tarkin, the character which Peter Cushing had played 28 years earlier in A New Hope.

[11] He has also had guest roles on the series My Place, A Country Practice, All Saints, Water Rats, Stingers, Murder Call, Medivac,[2] Time Trax, and The Lost World (1999–2001).

They produced a theatrical piece called Rush, which was written and performed by Pygram, Samantha Dowdeswell, and Dominique Sweeney,[15] at the Riverina Playhouse in 2020.

[6] Pygram has played the drums in numerous bands, including with Farscape co-star Anthony Simcoe in Signal Room.

He toured southeast Asia with the dance collective Kix Interactive, and did drumming work for Kodak, Visa Corporation, Foster's, and Heineken.