It serves as the home of the Wayne State Warriors (NCAA Division II) men's and women's basketball teams and the Motor City Cruise of the NBA G League.

[4] Xtreme Fighting Championships held the XFC Detroit Grand Prix, the first mixed martial arts card at the arena, on June 2, 2023, headlined by John Lopez vs. Matt Lagou.

[6] TNA Wrestling held their Bound for Glory pay-per-view event at the arena on October 26, 2024, followed by the tapings of future episodes of their weekly shows Impact!

and Xplosion the next day, making these two events the first professional wrestling shows that the Wayne State Fieldhouse has hosted.

Plans for Wayne State Fieldhouse were announced less than 12 hours before the University Board met to sign the contract.