They were conducted by Department K, which turned willing and unwilling beings into living weapons to carry out covert missions like assassination or eliminating potential threats to the government.
The Weapon X organization was created by writer Len Wein and artist Herb Trimpe, and first appeared in The Incredible Hulk #180 (October 1974).
The code name Weapon X was originally mentioned in the first appearance of Wolverine in The Incredible Hulk #180 in 1974 since which it has been implied that he was connected to a shady and malevolent government program.
In the 1991 story arc "Weapon X" (originally published in Marvel Comics Presents #72–84 in 1991), the project was designated Experiment X, and it was revealed that it was responsible for bonding the adamantium to Wolverine's skeleton, making him indestructible.
Wolverine's solo series issues #48-50 (1992) revealed that Project X also created fabricated memories in the minds of several of its subjects.
A smaller experiment was later developed by Department K with a New Zealand terrorist (who would become the third individual to be known as Weapon X) merging him with Thetagen-24: the most dangerous lethal symbiotic bacterial colony ever created.
Typhoid Mary was also a subject, when she was captured by an Antarctic facility continuing research for the Weapon X Project, specifically the mental faculties of the mutant mind.
Colcord, once a security guard at the first Weapon X project, suffered severe facial lacerations during an escape attempt by the mutant Wolverine.
A number of mutants, such as Cecilia Reyes, Maggott, Ape, Tarbaby, Leech and many others were arrested by Weapon X's agents and sent to Neverland.
Former mutant terrorist Marrow had her powers set to a controllable level, restoring the young woman's natural beauty.
Aurora was kidnapped and brainwashed, like Madison Jeffries, who was extracted from the terrorist group known as the Zodiac and used to create hundreds of Boxbots loyal to Weapon X to serve as guards at Neverland.
Mesmero joins willingly, while Reaper and Wildside (former members of the Mutant Liberation Front) became agents of the program in exchange for their lives.
Unbeknownst to all except Sabretooth, Mister Sinister was disguised as the head scientist at the Neverland facility, Doctor Robert Windsor.
Marrow used the battle to escape from Weapon X, eventually taking over the Mutant Underground, now reformed as the third incarnation of Gene Nation.
Director Brent Jackson's team consisted of Wildchild, Sauron, Agent Zero, Mesmero, Jack-in-the-Box, and newly recruited Chamber, whose face was restored by the program's scientists.
It is shown that the Weapon X Project is turning civilians into cyborgs made of Adamantium sent to hunt a specific group of mutants, forcing Old Man Logan to team up with Sabretooth to stop them.
Following the fierce battle, H-Alpha flees causing Old Man Logan's group to go after it before the Weapon X Project plans to regain control of it.
[7] Following Professor Charles Xavier founding a sovereign nation state for mutants on the living island Krakoa, he made sure all shadow agencies around the world were defunded and disbanded, Weapon X among them.
[8] However remnants of those agencies gathered together and established Xeno a global organization with ties to anti-mutant politicians and business leaders.
Domino was discovered during her infiltration, and The Xeno's operatives used grafts of her skin on their genetically altered soldiers to allow them to evade Krakoa's security protocols.
It was written by Frank Tieri, who previously wrote the ongoing Wolverine title and had created the group's most recent incarnation in the pages of said book.
However, sales sagged following the removal of Cable from the book after the first year, on orders of Rob Liefeld, who was working on a new X-Force project.
[citation needed] Frank Tieri was forced to drop nearly all of his subplots, including the introduction of a mutant concentration camp run by Mr. Sinister that featured many popular B-List mutant characters, and take the book into the controversial direction involving the introduction of X-23, and Wolverine and Sabretooth's quest to find the recently revived John Sublime.
[1] In the Age of Apocalypse alternate timeline, Logan was never actually called Wolverine; he retained the "Weapon X" codename, through his entire career.
At the time, the membership of Weapon X consisted of Sabretooth (Victor Creed of the Age of Apocalypse, the father figure of the Exiles' leader Blink), Deadpool and Garrison Kane.
The six chose the name 'Weapon X' due to their common ties to the Project in their native timelines, although, save for Sabretooth, the background of all the other members are a mystery.
When the two teams met face-to-face for the first time, Weapon X was already a sextet: Sabretooth, Deadpool, the Spider (Peter Parker, an alternate version of Spider-Man, here a psychotic murderer with the symbiotic alien costume of Carnage), Storm (Ororo Munroe, here only sixteen years old and already ruler of more than half of Africa), the Vision (a version that remained an emotionless robot), and the Hulk (Jennifer Walters, normally called the She-Hulk, here a former mob bookkeeper transformed into an eight-foot green-skinned powerhouse).
In addition to having bone claws, enhanced senses and a healing factor, the elder Howlett appeared to have some kind of ethereal form which allowed him to phase through things and somehow conduct energy blasts.
Set in Marvel Noir, this Weapon X is a 1940s German based government agency led by the "Red Rose"/Jiamine Szardos/Amanda Selfron, a former circus artist.