In June 1892, a letter written by Kirtley was published in the Sunderland Daily Post and The Herald in which he stated that he had been asked by several club secretaries about the possibility of forming an organisation to play home-and-home matches, so as to find out which was the best amateur team.

At a meeting soon afterwards at the Central Coffee Tavern, eleven clubs agreed to form a league, which commenced playing later that year.

After the Great War, the league was dominated for many years by colliery welfare teams – in the 1930s every league title was won by a pit team and the mining clubs continued to dominate right through to the 1970s, although an increasing number began to experience financial difficulties from the 1950s onwards due to shrinking workforces at the mines.

In 1978 Blue Star became the first Wearside League club to reach the final of the FA Vase, and went on to win the trophy, the start of a run of success which would ultimately see them progress much higher up the non-league ranks.

More recently, clubs such as Darlington Railway Athletic, North Shields, Newton Aycliffe, Ryhope Colliery Welfare and Willington have successfully moved up to the Northern League.