The Crewe–Liverpool line is a railway line in North West England that diverges from the West Coast Main Line at Weaver Junction 16 miles 53 chains (26.8 km) north of Crewe and runs to Liverpool Lime Street via Runcorn and Liverpool South Parkway.

The line was electrified at 25 kV AC, using overhead wires under the BR 1955 Modernisation Plan.

In 1959, preparations began at Liverpool Lime Street for the first stage of electrification of the West Coast Main Line.

[1] On 1 January 1962, electric services between Liverpool Lime Street and Crewe officially began.

[3] Services along the full length of the line are operated by Avanti West Coast and London Northwestern Railway, with East Midlands Railway, Northern and TransPennine Express operating between Liverpool South Parkway and Lime Street, a section which is shared by the Liverpool–Manchester lines.