Weber–Christian disease is a cutaneous condition characterized by recurrent subcutaneous nodules that heal with depression of the overlying skin.

[2] It is a rare disease seen in females 30–60 years of age.

It is a recurring inflammation of fatty layers of tissue present beneath the skin.

Lesions are bilaterally symmetrical and are usually seen in the lower legs.

[citation needed] It is named after[3] Frederick Parkes Weber[4] and Henry Asbury Christian.