[17] Weequahic High School has an active alumni association that raises scholarship monies for the students.

[19] The Weequahic High School Indians[2] compete in the Super Essex Conference, which is comprised of public and private high schools in Essex County and was established after a reorganization of sports leagues in Northern New Jersey under the supervision of the New Jersey State Interscholastic Athletic Association (NJSIAA).

[22] The football team competes in the National White division of the North Jersey Super Football Conference, which includes 112 schools competing in 20 divisions, making it the nation's biggest football-only high school sports league.

A crowd of 4,500 watched as the 1962 team won the Group IV title with a 55–52 victory against Westfield in the championship game to finish the season with a record of 24–3.

[28] A 62–38 win against Hackensack in the championship game played at Convention Hall in Atlantic City gave the team a 25-1 season record and the Group IV state title.

[32] The 2002 boys' basketball won the North II, Group III state sectional championship, edging West Side High School in the tournament final.

In 2016, in the first sectional title game played between two Newark high schools, the football team defeated Malcolm X Shabazz High School by a score of 18–8 to win the North II, Group I championship, the program's second sectional title in the playoff era.

[36] The 2011 game was the 29th between the two teams, ending in a 27–20 win for Weequahic, which won its fifth consecutive defeat of Shabazz.

[41] The high school newspaper is The Calumet, the literary magazine is Ergo, and the yearbook is called The Legend.