Sportswriters named him a first-team All-American after the Rice Owls finished with an 8–2 win–loss record and beat Tennessee 8–0 in the 1947 Orange Bowl.

Humble became an anchor on Cleveland's offensive line, helping the team win three straight AAFC titles in the late 1940s.

He was expected to return to Cleveland the following year, but head coach Paul Brown traded him to the Texans before the 1952 season began.

[3] He also played on the basketball, track and swimming teams before graduating and enrolling at Rice University in Houston, Texas in 1940.

[3] Captained by Humble, Southwestern beat a service team from Randolph Air Force Base in San Antonio.

He lettered in football and track and field and was voted a consensus first-team All-American guard while captain of Rice's Southwest Conference co-champion team.

[2] He was also named lineman of the week by the Associated Press in November for his strong tackling in a game against the Texas A&M Aggies.

[14] In Cleveland, Humble was part of an offensive line that included Lin Houston, Ed Ulinski and Bob Gaudio.

[15] Their job was to protect quarterback Otto Graham from opposing defenders and open up running room for fullback Marion Motley.

[15] Helped by strong line play, Graham, Motley and Cleveland ends Dante Lavelli and Mac Speedie led a potent offense that dominated the AAFC for three years.

[15] The Browns finished the season with a 10–2 record and beat the Los Angeles Rams in the NFL championship game.

[23] The trade was unexpected because Cleveland's other guards, including Gaudio and Alex Agase, were getting older and nearing retirement.

[10][26] He later became vice-president of an office supply firm called Stationers, Inc.[10][24] He maintained an affiliation with his Texas alma mater, serving as president and later director of the R Association, an alumni group for former Rice student-athletes.

[29] He was included on a 50th anniversary All-Southwest Conference team in 1968, and in 1970 was one of the first people inducted into the Rice University Athletics Hall of Fame.

[31] Later in life, Humble worked for the Harris County Appraisal Review Board and was a salesman for an office furniture supply company.