Principal investigators working at the Centre include Professors Ray Dolan, Jon Driver, Richard Frackowiak, Chris Frith, Karl Friston, Eleanor Maguire, Cathy Price, and Geraint Rees.

The Centre is located in Queen Square in the Bloomsbury area of Central London, adjacent to the National Hospital for Neurology and Neurosurgery.

The award enabled a core group of scientists, based at the Medical Research Council Cyclotron Unit, at the Hammersmith Hospital to relocate their activity to a central London site, within UCL.

Over the next decade functional magnetic resonance imaging (fMRI) became the primary investigative tool of the FIL, leading to PET decommissioning in 2004.

Currently, the investigative tools of the laboratory include functional magnetic resonance imaging (fMRI) magneto-encephalography (MEG) and electro-encephalography (EEG).