As a freshman in 2015–16, he started in all 29 games played and averaged 17.9 points, 8.6 rebounds, 3.3 assists and 1.8 steals to help his team to a 22–8 record and a sectional championship.

As a sophomore in 2016–17, he started in all 33 games and averaged 25.0 points, 9.2 rebounds, 3.9 assists and 2.3 steals to help his team to a 27–6 record and a 3A state title.

On October 8, 2018, Moore announced that he would attend Duke University and play for the Blue Devils during the 2019–20 season.

He hit a putback shot after a Tre Jones miss to give the Blue Devils a 98–96 win.

[12] On November 12, 2021, Moore recorded 19 points, 10 rebounds and 10 assists, making him the fifth player in Blue Devils history with a triple-double.