Jacob has created installations and interventions in social spaces since 1989, and has developed a distinct body of sculptural works which investigate the interface between architecture and the bodies of the people and animals who inhabit the built environment.
[citation needed] She is also a member of the Chicago-based collaborative Haha, whose work focuses on the exploration of social positions relative to a particular site, and which has produced over two dozen influential projects since the late 1980s.
[4] One of Jacob's collaborations has been the creation of the Squeeze Chair, inspired by Temple Grandin's hug machine.
[5][6][7] Jacob has had solo exhibitions at Jacob's work resides in the collections of Centre Georges-Pompidou, Paris, France; Fonds Regional d'Art Contemporain (fr), Poitou-Charentre, Poitier, France; Fonds Regional d'Art Contemporain, Languedoc-Roussillon, Montpellier, France; Museum of Contemporary Art, San Diego, California; and the MacArthur Foundation, Chicago, Illinois.
[citation needed] Jacob received the Creative Capital Visual Arts Award in the year 2000.